pentobarbital will reduce the level or influence of pimavanserin by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Check. Avoid coadministration if possible. Monitor for diminished pimavanserin efficacy. A rise in pimavanserin dosage could be wanted.
fentanyl transdermal and pentobarbital each improve sedation. Stay clear of or Use Alternate Drug. Restrict use to people for whom alternate cure solutions are inadequate
pentobarbital will minimize the level or outcome of nelfinavir by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Observe.
pentobarbital will lower the level or effect of larotrectinib by impacting hepatic/intestinal enzyme CYP3A4 metabolism.
pentobarbital will minimize the level or outcome of sunitinib by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Observe.
Scientific tests in young animals and children have proven that Repeated or long-phrase utilization of anesthesia drugs or medicines employed for slumber in kids more youthful than 3 yrs of age could lead to long-phrase brain problems.
Contraindicated (1)pentobarbital will decrease the extent or effect of doravirine by influencing hepatic/intestinal enzyme CYP3A4 metabolism.
fentanyl transmucosal and pentobarbital equally maximize sedation. Keep away from or Use Alternate Drug. Limit use to patients for whom alternate cure alternatives are inadequate
In the event the buprenorphine dose is inadequate and the CYP3A4 inducer can't be lowered or discontinued, changeover the affected individual again to some buprenorphine formulation that allows dose adjustments.
pentobarbital will decrease the level or result of prednisone by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Check.
pentobarbital will minimize the extent or result of ondansetron by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor. No dosage adjustment for ondansetron is recommended for patients on these prescription drugs.
pentobarbital will decrease the extent or impact of lumacaftor/ivacaftor by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated.
This drug may possibly boost the metabolism of estradiol when administered concurrently; people on oral contraceptives are becoming pregnant when more info concurrently dealt with with antiepileptic drugs; advise an alternate contraceptive process to Women of all ages using this drug
Monoamine oxidase inhibitors (MAOI) may well inhibit barbiturate metabolism and extend barbiturate effects; keep an eye on carefully